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Proteolytic processing of Middle East respiratory syndrome coronavirus spikes expands virus tropism
Middle East respiratory syndrome coronavirus (MERS-CoV) infects humans from zoonotic sources and causes severe pulmonary disease. Virions require spike (S) glycoproteins for binding to cell receptors and for catalyzing virus–cell membrane fusion. Fusion occurs only after S proteins are cleaved seque...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5086990/ https://ncbi.nlm.nih.gov/pubmed/27791014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608147113 |
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