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Ductular reaction-on-a-chip: Microfluidic co-cultures to study stem cell fate selection during liver injury

Liver injury modulates local microenvironment, triggering production of signals that instruct stem cell fate choices. In this study, we employed a microfluidic co-culture system to recreate important interactions in the liver stem cell niche, those between adult hepatocytes and liver progenitor cell...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Haque, Amranul, Gheibi, Pantea, Stybayeva, Gulnaz, Gao, Yandong, Torok, Natalie, Revzin, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086854/
https://ncbi.nlm.nih.gov/pubmed/27796316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36077
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