Interleukin 15 is produced by endothelial cells and increases the transendothelial migration of T cells In vitro and in the SCID mouse-human rheumatoid arthritis model In vivo.

The capacity of endothelial cells (EC) to produce IL-15 and the capacity of IL-15 to influence transendothelial migration of T cells was examined. Human umbilical vein endothelial cells expressed both IL-15 mRNA and protein. Moreover, endothelial-derived IL-15 enhanced transendothelial migration of...

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Vydáno v:J Clin Invest
Hlavní autoři: Oppenheimer-Marks, N, Brezinschek, R I, Mohamadzadeh, M, Vita, R, Lipsky, P E
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1998
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508680/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9502767/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI1986
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