טוען...

Identification of the low density lipoprotein receptor-binding site in apolipoprotein B100 and the modulation of its binding activity by the carboxyl terminus in familial defective apo-B100.

Familial defective apolipoprotein B100 (FDB) is caused by a mutation of apo-B100 (R3500Q) that disrupts the receptor binding of low density lipoproteins (LDL), which leads to hypercholesterolemia and premature atherosclerosis. In this study, mutant forms of human apo-B were expressed in transgenic m...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Clin Invest
Main Authors: Boren, J, Lee, I, Zhu, W, Arnold, K, Taylor, S, Innerarity, T L
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 1998
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508660/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9486979/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI1847
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