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Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2.
Heme oxygenase (HO) activity leads to accumulation of the antioxidant bilirubin, and degradation of the prooxidant heme. Moderate overexpression of the inducible form, HO-1, is associated with protection against oxidative injury. However, the role of HO-2 in oxidative stress has not been explored. W...
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Hoofdauteurs: | , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
1998
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC508651/ https://ncbi.nlm.nih.gov/pubmed/9486970 |
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