Effector protease receptor 1 mediates the mitogenic activity of factor Xa for vascular smooth muscle cells in vitro and in vivo.

The binding of 125I-factor Xa to human aortic smooth muscle cell (SMC) monolayers was studied. At 4 degreesC, 125I-factor Xa bound to a single class of binding sites with a dissociation constant value of 3.6+/-0.7 nM and a binding site density of 11,720+/-1,240 sites/cell (n = 9). 125I-factor Xa bin...

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Main Authors: Herbert, J, Bono, F, Herault, J, Avril, C, Dol, F, Mares, A, Schaeffer, P
格式: Artigo
語言:Inglês
出版: 1998
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC508650/
https://ncbi.nlm.nih.gov/pubmed/9486969
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