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Protection against myocardial dysfunction after a brief ischemic period in transgenic mice expressing inducible heat shock protein 70.

Brief ischemic periods lead to myocardial dysfunction without myocardial infarction. It has been shown that expression of inducible HSP70 in hearts of transgenic mice leads to decreased infarct size, but it remains unclear if HSP70 can also protect against myocardial dysfunction after brief ischemia...

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Udgivet i:J Clin Invest
Principais autores: Trost, S U, Omens, J H, Karlon, W J, Meyer, M, Mestril, R, Covell, J W, Dillmann, W H
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1998
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508634/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9466981/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI265
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