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Statin Derivatives as Therapeutic Agents for Castration-Resistant Prostate Cancer

Despite recent advances in modern medicine, castration-resistant prostate cancer remains an incurable disease. Subpopulations of prostate cancer cells develop castration-resistance by obtaining the complete steroidogenic ability to synthesize androgens from cholesterol. Statin derivatives, such as s...

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Bibliografische gegevens
Gepubliceerd in:Cancer Lett
Hoofdauteurs: Ingersoll, Matthew A., Miller, Dannah R., Martinez, October, Wakefield, C. Brent, Hsieh, Kuan-Chan, Simha, M. Vijaya, Kao, Chai-Lin, Chen, Hui-Ting, Batra, Surinder K., Lin, Ming-Fong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086260/
https://ncbi.nlm.nih.gov/pubmed/27687622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.09.008
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