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Phosphorylation of C/EBP Homologous Protein (CHOP) by the AMP-Activated Protein Kinase Alpha 1 in Macrophages Promotes CHOP Degradation and Reduces Injury-Induced Neointimal Disruption In Vivo

RATIONALE: Elevated levels of C/EBP homologous protein (CHOP), a member of the C/EBP transcription factor family, in advanced atherosclerotic plaques is reported to be associated with atherosclerotic plaque rupture in humans. However, the molecular mechanism by which CHOP accumulation occurs is poor...

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Dades bibliogràfiques
Publicat a:Circ Res
Autors principals: Dai, Xiaoyan, Ding, Ye, Liu, Zhaoyu, Zhang, Wencheng, Zou, Ming-Hui
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085850/
https://ncbi.nlm.nih.gov/pubmed/27650555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.309463
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