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Decorin suppresses tumor cell growth by activating the epidermal growth factor receptor.

Decorin, a small leucine-rich proteoglycan, is capable of suppressing the growth of various tumor cell lines when expressed ectopically. In this report, we investigated the biochemical mechanism by which decorin inhibits cell cycle progression. In A431 squamous carcinoma cells, decorin proteoglycan...

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Main Authors: Moscatello, D K, Santra, M, Mann, D M, McQuillan, D J, Wong, A J, Iozzo, R V
Formato: Artigo
Idioma:Inglês
Publicado: 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC508580/
https://ncbi.nlm.nih.gov/pubmed/9435313
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