The role of interleukin-converting enzyme in Fas-mediated apoptosis in HIV-1 infection.

Apoptosis of CD4+ lymphocytes is partially responsible for the depletion of these cells in HIV-infected individuals. CD4+ lymphocytes from HIV-1-infected patients express higher membrane levels of the Fas receptor, and are particularly susceptible to apoptosis after Fas triggering. IL-1beta- convert...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Sloand, E M, Maciejewski, J P, Sato, T, Bruny, J, Kumar, P, Kim, S, Weichold, F F, Young, N S
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1998
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508556/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9421482/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI530
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