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Adiponectin and heme oxygenase-1 suppress TLR4/MyD88-independent signaling in rat Kupffer cells and in mice after chronic ethanol exposure
Alcoholic liver disease (ALD) is mediated via activation of TLR-4 signaling; MyD88-dependent and -independent signals are important contributors to injury in mouse models. Adiponectin, an anti-inflammatory adipokine, suppresses TLR-4/MyD88-dependent responses via induction of heme oxygenase-1 (HO-1)...
Guardat en:
| Publicat a: | J Immunol |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5085268/ https://ncbi.nlm.nih.gov/pubmed/20861358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002060 |
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