STING-Licensed Macrophages Prime Type I IFN Production by Plasmacytoid Dendritic Cells in the Bone Marrow during Severe Plasmodium yoelii Malaria

Malaria remains a global health burden causing significant morbidity, yet the mechanisms underlying disease outcomes and protection are poorly understood. Herein, we analyzed the peripheral blood of a unique cohort of Malawian children with severe malaria, and performed a comprehensive overview of b...

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Vydáno v:PLoS Pathog
Hlavní autoři: Spaulding, Emily, Fooksman, David, Moore, Jamie M., Saidi, Alex, Feintuch, Catherine M., Reizis, Boris, Chorro, Laurent, Daily, Johanna, Lauvau, Grégoire
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085251/
https://ncbi.nlm.nih.gov/pubmed/27792766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005975
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