Solid tumors provide niche-specific conditions that lead to preferential growth of Salmonella

Therapeutic attenuated strains of Salmonella Typhimurium target and eradicate tumors in mouse models. However, the mechanism of S. Typhimurium for tumor targeting is still poorly understood. We performed a high-throughput screening of single-gene deletion mutants of S. Typhimurium in an orthotopic,...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Silva-Valenzuela, Cecilia A., Desai, Prerak T., Molina-Quiroz, Roberto C., Pezoa, David, Zhang, Yong, Porwollik, Steffen, Zhao, Ming, Hoffman, Robert M., Contreras, Inés, Santiviago, Carlos A., McClelland, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085218/
https://ncbi.nlm.nih.gov/pubmed/27145267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9071
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