Identification of genes that are essential to restrict genome duplication to once per cell division

Nuclear genome duplication is normally restricted to once per cell division, but aberrant events that allow excess DNA replication (EDR) promote genomic instability and aneuploidy, both of which are characteristics of cancer development. Here we provide the first comprehensive identification of gene...

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Foilsithe in:Oncotarget
Main Authors: Vassilev, Alex, Lee, Chrissie Y., Vassilev, Boris, Zhu, Wenge, Ormanoglu, Pinar, Martin, Scott E., DePamphilis, Melvin L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2016
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085202/
https://ncbi.nlm.nih.gov/pubmed/27144335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9008
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