N-n-butyl haloperidol iodide ameliorates hypoxia/reoxygenation injury through modulating the LKB1/AMPK/ROS pathway in cardiac microvascular endothelial cells

Endothelial cells are highly sensitive to hypoxia and contribute to myocardial ischemia/reperfusion injury. We have reported that N-n-butyl haloperidol iodide (F(2)) can attenuate hypoxia/reoxygenation (H/R) injury in cardiac microvascular endothelial cells (CMECs). However, the molecular mechanisms...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lu, Binger, Wang, Bin, Zhong, Shuping, Zhang, Yanmei, Gao, Fenfei, Chen, Yicun, Zheng, Fuchun, Shi, Ganggang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085190/
https://ncbi.nlm.nih.gov/pubmed/27166184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9186
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