Asparaginyl endopeptidase promotes the invasion and metastasis of gastric cancer through modulating epithelial-to-mesenchymal transition

Asparaginyl endopeptidase (AEP) is a lysosomal protease often overexpressed in gastric cancer. AEP was expressed higher in peritoneal metastatic loci than in primary gastric cancer. Then we overexpressed AEP or knocked it down with a lentiviral vector in gastric cancer cell lines and detected the ce...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Cui, Yuehong, Wang, Yan, Li, Hong, Li, Qian, Yu, Yiyi, Xu, Xiaojing, Xu, Bei, Liu, Tianshu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085161/
https://ncbi.nlm.nih.gov/pubmed/27102302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8879
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