Genetic alterations and protein expression in combined small cell lung cancers and small cell lung cancers arising from lung adenocarcinomas after therapy with tyrosine kinase inhibitors

There are 2 hypotheses regarding the mechanism underlying the adenocarcinoma (AD) to small cell lung cancer (SCLC) transition in patients receiving Tyrosine kinase inhibitor (TKI) therapy: 1) AD gives rise to SCLC owing to the pressure of the TKI therapy, and 2) the SCLC coexists with the AD de novo...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Shi, Xiaohua, Duan, Huanli, Liu, Xuguang, Zhou, Liangrui, Liang, Zhiyong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085152/
https://ncbi.nlm.nih.gov/pubmed/27145273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9083
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