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Rheb may complex with RASSF1A to coordinate Hippo and TOR signaling

The TOR pathway is a vital component of cellular homeostasis that controls the synthesis of proteins, nucleic acids and lipids. Its core is the TOR kinase. Activation of the TOR pathway suppresses autophagy, which plays a vital but complex role in tumorigenesis. The TOR pathway is regulated by activ...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Nelson, Nicholas, Clark, Geoffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085121/
https://ncbi.nlm.nih.gov/pubmed/27034171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8447
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