HCV core protein binds to gC1qR to induce A20 expression and inhibit cytokine production through MAPKs and NF-κB signaling pathways

Hepatitis C virus (HCV) infection is characterized by a strong propensity toward chronicity. During chronic HCV infection, HCV core protein is implicated in deregulating cytokine expression that associates with chronic inflammation. A20 is known as a powerful suppressor in cytokine signaling, in thi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Song, Xiaotian, Yao, Zhiyan, Yang, Jianling, Zhang, Zhengzheng, Deng, Yuqing, Li, Miao, Ma, Cuiqing, Yang, Lijuan, Gao, Xue, Li, Wenjian, Liu, Jianguo, Wei, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper: Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085119/
https://ncbi.nlm.nih.gov/pubmed/27183919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9304
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