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Cimetidine down-regulates stability of Foxp3 protein via Stub1 in Treg cells

Foxp3-expressing Treg cells have been well documented to provide immune regulation by promoting immune tolerance and suppressing immune over-reaction. Cimetidine (CIM), used to inhibit stomach acid secretion, has been reported to promote immune responses and suppress Treg cell function in several st...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Zhang, Yizhi, Chen, Zhoujia, Luo, Xuerui, Wu, Bin, Li, Bin, Wang, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085004/
https://ncbi.nlm.nih.gov/pubmed/27324694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2016.1191719
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