Troglitazone action is independent of adipose tissue.

We have investigated the antidiabetic action of troglitazone in aP2/DTA mice, whose white and brown fat was virtually eliminated by fat-specific expression of diphtheria toxin A chain. aP2/DTA mice had markedly suppressed serum leptin levels and were hyperphagic, but did not gain excess weight. aP2/...

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Autori principali: Burant, C F, Sreenan, S, Hirano, K, Tai, T A, Lohmiller, J, Lukens, J, Davidson, N O, Ross, S, Graves, R A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC508497/
https://ncbi.nlm.nih.gov/pubmed/9389757
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