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Microbiota-Derived Phenylacetylglutamine Associates with Overall Mortality and Cardiovascular Disease in Patients with CKD

Colonic microbial metabolism substantially contributes to uremic solute production. p-Cresyl sulfate and indoxyl sulfate are the main representatives of solutes of microbial origin and also, protein-bound solutes, exhibiting high protein-binding affinity and dependence on tubular secretion. Phenylac...

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Dettagli Bibliografici
Pubblicato in:J Am Soc Nephrol
Autori principali: Poesen, Ruben, Claes, Kathleen, Evenepoel, Pieter, de Loor, Henriette, Augustijns, Patrick, Kuypers, Dirk, Meijers, Björn
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084895/
https://ncbi.nlm.nih.gov/pubmed/27230658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015121302
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