Determining the Optimal Protocol for Measuring an Albuminuria Class Transition in Clinical Trials in Diabetic Kidney Disease

Albuminuria class transition (normo- to micro- to macroalbuminuria) is used as an intermediate end point to assess renoprotective drug efficacy. However, definitions of such class transition vary between trials. To determine the most optimal protocol, we evaluated the approaches used in four clinica...

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Veröffentlicht in:J Am Soc Nephrol
Hauptverfasser: Kröpelin, Tobias F., de Zeeuw, Dick, Remuzzi, Giuseppe, Bilous, Rudy, Parving, Hans-Henrik, Heerspink, Hiddo J.L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2016
Schlagworte:
Clinical Epidemiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084894/
https://ncbi.nlm.nih.gov/pubmed/27056294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015101150
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