CD103(+) Kidney Dendritic Cells Protect against Crescentic GN by Maintaining IL-10–Producing Regulatory T Cells

Kidney dendritic cells (DCs) regulate nephritogenic T cell responses. Most kidney DCs belong to the CD11b(+) subset and promote crescentic GN (cGN). The function of the CD103(+) subset, which represents <5% of kidney DCs, is poorly understood. We studied the role of CD103(+) DCs in cGN using seve...

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Vydáno v:J Am Soc Nephrol
Hlavní autoři: Evers, Beatrix D.G., Engel, Daniel R., Böhner, Alexander M.C., Tittel, André P., Krause, Torsten A., Heuser, Christoph, Garbi, Natalio, Kastenmüller, Wolfgang, Mack, Matthias, Tiegs, Gisa, Panzer, Ulf, Boor, Peter, Ludwig-Portugall, Isis, Kurts, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2016
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084885/
https://ncbi.nlm.nih.gov/pubmed/27036736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015080873
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