A Gata2 dependent transcription network regulates uterine progesterone responsiveness and endometrial function

Altered progesterone responsiveness leads to female infertility and cancer, but underlying mechanisms remain unclear. Mice with uterine-specific ablation of Gata2 are infertile showing failures in embryo implantation, endometrial decidualization and uninhibited estrogen signaling. Gata2 deficiency r...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Rubel, Cory A., Wu, San-Pin, Lin, Lin, Wang, Tianyuan, Lanz, Rainer B., Li, Xilong, Kommagani, Ramakrishna, Franco, Heather L., Camper, Sally A., Tong, Qiang, Jeong, Jae-Wook, Lydon, John P., DeMayo, Francesco J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084852/
https://ncbi.nlm.nih.gov/pubmed/27783953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.093
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