Initiating sacubitril/valsartan (LCZ696) in heart failure: results of TITRATION, a double‐blind, randomized comparison of two uptitration regimens

AIMS: To assess the tolerability of initiating/uptitrating sacubitril/valsartan (LCZ696) from 50 to 200 mg twice daily (target dose) over 3 and 6 weeks in heart failure (HF) patients (ejection fraction ≤35%). METHODS AND RESULTS: A 5‐day open‐label run‐in (sacubitril/valsartan 50 mg twice daily) pre...

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Argitaratua izan da:Eur J Heart Fail
Egile Nagusiak: Senni, Michele, McMurray, John J.V., Wachter, Rolf, McIntyre, Hugh F., Reyes, Antonio, Majercak, Ivan, Andreka, Peter, Shehova‐Yankova, Nina, Anand, Inder, Yilmaz, Mehmet B., Gogia, Harinder, Martinez‐Selles, Manuel, Fischer, Steffen, Zilahi, Zsolt, Cosmi, Franco, Gelev, Valeri, Galve, Enrique, Gómez‐Doblas, Juanjo J., Nociar, Jan, Radomska, Maria, Sokolova, Beata, Volterrani, Maurizio, Sarkar, Arnab, Reimund, Bernard, Chen, Fabian, Charney, Alan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley & Sons, Ltd 2016
Gaiak:
Medical Treatment
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084812/
https://ncbi.nlm.nih.gov/pubmed/27170530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejhf.548
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