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Initiating sacubitril/valsartan (LCZ696) in heart failure: results of TITRATION, a double‐blind, randomized comparison of two uptitration regimens

AIMS: To assess the tolerability of initiating/uptitrating sacubitril/valsartan (LCZ696) from 50 to 200 mg twice daily (target dose) over 3 and 6 weeks in heart failure (HF) patients (ejection fraction ≤35%). METHODS AND RESULTS: A 5‐day open‐label run‐in (sacubitril/valsartan 50 mg twice daily) pre...

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Bibliografiske detaljer
Udgivet i:Eur J Heart Fail
Main Authors: Senni, Michele, McMurray, John J.V., Wachter, Rolf, McIntyre, Hugh F., Reyes, Antonio, Majercak, Ivan, Andreka, Peter, Shehova‐Yankova, Nina, Anand, Inder, Yilmaz, Mehmet B., Gogia, Harinder, Martinez‐Selles, Manuel, Fischer, Steffen, Zilahi, Zsolt, Cosmi, Franco, Gelev, Valeri, Galve, Enrique, Gómez‐Doblas, Juanjo J., Nociar, Jan, Radomska, Maria, Sokolova, Beata, Volterrani, Maurizio, Sarkar, Arnab, Reimund, Bernard, Chen, Fabian, Charney, Alan
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084812/
https://ncbi.nlm.nih.gov/pubmed/27170530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejhf.548
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