Leptin rapidly suppresses insulin release from insulinoma cells, rat and human islets and, in vivo, in mice.

Obesity is associated with diabetes, and leptin is known to be elevated in obesity. To investigate whether leptin has a direct effect on insulin secretion, isolated rat and human islets and cultured insulinoma cells were studied. In all cases, mouse leptin inhibited insulin secretion at concentratio...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kulkarni, R N, Wang, Z L, Wang, R M, Hurley, J D, Smith, D M, Ghatei, M A, Withers, D J, Gardiner, J V, Bailey, C J, Bloom, S R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1997
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC508476/
https://ncbi.nlm.nih.gov/pubmed/9389736
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