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Exclusive transmission of the embryonic stem cell‐derived genome through the mouse germline

Gene targeting in embryonic stem (ES) cells remains best practice for introducing complex mutations into the mouse germline. One aspect in this multistep process that has not been streamlined with regard to the logistics and ethics of mouse breeding is the efficiency of germline transmission: the tr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genesis
Egile Nagusiak: Koentgen, Frank, Lin, Jiangwei, Katidou, Markella, Chang, Isabelle, Khan, Mona, Watts, Jacqui, Mombaerts, Peter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084746/
https://ncbi.nlm.nih.gov/pubmed/27012318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22938
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