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Exclusive transmission of the embryonic stem cell‐derived genome through the mouse germline
Gene targeting in embryonic stem (ES) cells remains best practice for introducing complex mutations into the mouse germline. One aspect in this multistep process that has not been streamlined with regard to the logistics and ethics of mouse breeding is the efficiency of germline transmission: the tr...
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| Veröffentlicht in: | Genesis |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5084746/ https://ncbi.nlm.nih.gov/pubmed/27012318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22938 |
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