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Deciphering the Substrate Specificity of SbnA, the Enzyme Catalyzing the First Step in Staphyloferrin B Biosynthesis

[Image: see text] Staphylococcus aureus assembles the siderophore, staphyloferrin B, from l-2,3-diaminopropionic acid (l-Dap), α-ketoglutarate, and citrate. Recently, SbnA and SbnB were shown to produce l-Dap and α-ketoglutarate from O-phospho-l-serine (OPS) and l-glutamate. SbnA is a pyridoxal 5′-p...

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Detalles Bibliográficos
Publicado en:Biochemistry
Main Authors: Kobylarz, Marek J., Grigg, Jason C., Liu, Yunan, Lee, Mathew S. F., Heinrichs, David E., Murphy, Michael E. P.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2016
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084695/
https://ncbi.nlm.nih.gov/pubmed/26794841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01045
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