Phase I, multicenter, open‐label, dose‐escalation study of sonidegib in Asian patients with advanced solid tumors

Sonidegib is a selective inhibitor of Smoothened receptor, which is a key regulator of the Hedgehog signaling pathway. The purpose of this study was to determine the maximum tolerated dose based on dose‐limiting toxicity (DLT) and the recommended dose (RD) of sonidegib in Asian patients with advance...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Minami, Hironobu, Ando, Yuichi, Ma, Brigette Buig Yue, Hsiang Lee, Jih‐, Momota, Hiroyuki, Fujiwara, Yutaka, Li, Leung, Fukino, Koichi, Ito, Koji, Tajima, Takeshi, Mori, Asuka, Lin, Chia‐Chi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084670/
https://ncbi.nlm.nih.gov/pubmed/27467121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13022
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker