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Peperomin E reactivates silenced tumor suppressor genes in lung cancer cells by inhibition of DNA methyltransferase

Advanced lung cancer has poor prognosis owing to its low sensitivity to current chemotherapy agents. Therefore, discovery of new therapeutic agents is urgently needed. In this study, we investigated the antitumor effects of peperomin E, a secolignan isolated from Peperomia dindygulensis, a frequentl...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Wang, Xin‐zhi, Cheng, Ying, Wang, Kui‐long, Liu, Rui, Yang, Xiao‐lin, Wen, Hong‐mei, Chai, Chuan, Liang, Jing‐yu, Wu, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084666/
https://ncbi.nlm.nih.gov/pubmed/27501331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13029
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