Protease-resistant form of insulin-like growth factor-binding protein 5 is an inhibitor of insulin-like growth factor-I actions on porcine smooth muscle cells in culture.

IGFs are pleiotrophic mitogens for porcine smooth muscle cells (pSMC) in culture. The effects of IGFs on cells are modulated by various insulin-like growth factor-binding proteins (IGFBP). IGFBP-5 is synthesized by pSMC and binds to the extracellular matrix. However, IGFBP-5 is also secreted into co...

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Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Imai, Y, Busby, W H, Smith, C E, Clarke, J B, Garmong, A J, Horwitz, G D, Rees, C, Clemmons, D R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 1997
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508461/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9366575/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119803
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