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Pulsatile insulin release from pancreatic islets with nonoscillatory elevation of cytoplasmic Ca2+.
The relationship between insulin release and cytoplasmic Ca2+ concentration ([Ca2+]i) was studied in isolated pancreatic islets from ob/ob mice. Although [Ca2+]i was low and stable in the presence of 3 mM glucose, basal insulin release exhibited low amplitude pulsatility, with a frequency of 0.32 +/...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508455/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9366569/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119797 |
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