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Adaptive Pre-specification in Randomized Trials With and Without Pair-Matching

In randomized trials, adjustment for measured covariates during the analysis can reduce variance and increase power. To avoid misleading inference, the analysis plan must be pre-specified. However, it is often unclear a priori which baseline covariates (if any) should be adjusted for in the analysis...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: Balzer, Laura B., van der Laan, Mark J., Petersen, Maya L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084457/
https://ncbi.nlm.nih.gov/pubmed/27436797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7023
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