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Differences in systemic adaptive immunity contribute to the ‘frequent exacerbator’ COPD phenotype

BACKGROUND: Some COPD patients are more susceptible to exacerbations than others. Mechanisms underlying these differences in susceptibility are not well understood. We hypothesized that altered cell mediated immune responses may underlie a propensity to suffer from frequent exacerbations in COPD. ME...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Geerdink, Jasper X., Simons, Sami O., Pike, Rebecca, Stauss, Hans J., Heijdra, Yvonne F., Hurst, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084432/
https://ncbi.nlm.nih.gov/pubmed/27793198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0456-y
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