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Epidermal growth factor prevents APOE4 and amyloid-beta-induced cognitive and cerebrovascular deficits in female mice

Cerebrovascular (CV) dysfunction is emerging as a critical component of Alzheimer’s disease (AD), including altered CV coverage. Angiogenic growth factors (AGFs) are key for controlling CV coverage, especially during disease pathology. Therefore, evaluating the effects of AGFs in vivo can provide im...

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Publicat a:Acta Neuropathol Commun
Autors principals: Thomas, Riya, Zuchowska, Paulina, Morris, Alan W. J., Marottoli, Felecia M., Sunny, Sangeeta, Deaton, Ryan, Gann, Peter H., Tai, Leon M.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084423/
https://ncbi.nlm.nih.gov/pubmed/27788676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0387-3
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