Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER

Exosomes are nanovesicles released by virtually all cells, which act as intercellular messengers by transfer of protein, lipid, and RNA cargo. Their quantitative efficiency, routes of cell uptake, and subcellular fate within recipient cells remain elusive. We quantitatively characterize exosome cell...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Heusermann, Wolf, Hean, Justin, Trojer, Dominic, Steib, Emmanuelle, von Bueren, Stefan, Graff-Meyer, Alexandra, Genoud, Christel, Martin, Katrin, Pizzato, Nicolas, Voshol, Johannes, Morrissey, David V., Andaloussi, Samir E.L., Wood, Matthew J., Meisner-Kober, Nicole C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084269/
https://ncbi.nlm.nih.gov/pubmed/27114500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201506084
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