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Multifunctional actions of approved and candidate stroke drugs

Ischemic stroke causes brain damage by multiple pathways. Previous stroke trials have demonstrated that drugs targeting one or only a few of these pathways fail to improve clinical outcome after stroke. Drugs with multimodal actions have been suggested to overcome this challenge. In this review, we...

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Опубликовано в: :Neurotherapeutics
Главные авторы: Minnerup, Jens, Schäbitz, Wolf-Rüdiger
Формат: Artigo
Язык:Inglês
Опубликовано: Springer-Verlag 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084255/
https://ncbi.nlm.nih.gov/pubmed/19110198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nurt.2008.10.032
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