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Granulocyte-colony stimulating factor for stroke treatment: mechanisms of action and efficacy in preclinical studies

G-CSF is widely employed for the treatment of chemotherapy-induced neutropenia. Recently, neuroprotective effects of G-CSF in animal stroke models were discovered including infarct size reduction and enhancement of functional recovery. The underlying mechanisms of action of G-CSF in ischemia appear...

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Detalhes bibliográficos
Main Authors: Minnerup, Jens, Sevimli, Sevgi, Schäbitz, Wolf-Rüdiger
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816868/
https://ncbi.nlm.nih.gov/pubmed/20142989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2040-7378-1-2
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