Pretreatment with antibody to eosinophil major basic protein prevents hyperresponsiveness by protecting neuronal M2 muscarinic receptors in antigen-challenged guinea pigs.

In antigen-challenged guinea pigs there is recruitment of eosinophils into the lungs and to airway nerves, decreased function of inhibitory M2 muscarinic autoreceptors on parasympathetic nerves in the lungs, and airway hyperresponsiveness. A rabbit antibody to guinea pig eosinophil major basic prote...

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Publikašuvnnas:	J Clin Invest
Váldodahkkit:	Evans, C M, Fryer, A D, Jacoby, D B, Gleich, G J, Costello, R W
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	American Society for Clinical Investigation 1997
Fáttát:	Research Article
Liŋkkat:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508421/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9410903/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119763
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