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The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor.

Lp(a) is a major inherited risk factor associated with premature heart disease and stroke. The mechanism of Lp(a) atherogenicity has not been elucidated, but likely involves both its ability to influence plasminogen activation as well as its atherogenic potential as a lipoprotein particle after rece...

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Bibliographische Detailangaben
Hauptverfasser: Argraves, K M, Kozarsky, K F, Fallon, J T, Harpel, P C, Strickland, D K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC508411/
https://ncbi.nlm.nih.gov/pubmed/9410893
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