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Aspartyl Oxidation Catalysts That Dial In Functional Group Selectivity, along with Regio- and Stereoselectivity

[Image: see text] A remarkable aspect of enzyme evolution is the portability of catalytic mechanisms for fundamentally different chemical reactions. For example, aspartyl proteases, which contain two active site carboxylic acid groups, catalyze the hydrolysis of amide bonds, while glycosyltransferas...

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Detalhes bibliográficos
Publicado no:ACS Cent Sci
Main Authors: Alford, Joshua S., Abascal, Nadia C., Shugrue, Christopher R., Colvin, Sean M., Romney, David K., Miller, Scott J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084076/
https://ncbi.nlm.nih.gov/pubmed/27800556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.6b00237
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