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Aspartyl Oxidation Catalysts That Dial In Functional Group Selectivity, along with Regio- and Stereoselectivity

[Image: see text] A remarkable aspect of enzyme evolution is the portability of catalytic mechanisms for fundamentally different chemical reactions. For example, aspartyl proteases, which contain two active site carboxylic acid groups, catalyze the hydrolysis of amide bonds, while glycosyltransferas...

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Bibliografski detalji
Izdano u:ACS Cent Sci
Glavni autori: Alford, Joshua S., Abascal, Nadia C., Shugrue, Christopher R., Colvin, Sean M., Romney, David K., Miller, Scott J.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2016
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084076/
https://ncbi.nlm.nih.gov/pubmed/27800556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.6b00237
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