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Maternal Folate Status and the BHMT c.716G>A Polymorphism Affect the Betaine Dimethylglycine Pathway during Pregnancy

The effect of the betaine: homocysteine methyltransferase BHMT c.716G>A (G: guanosine; A: adenosine) single nucleotide polymorphism (SNP) on the BHMT pathway is unknown during pregnancy. We hypothesised that it impairs betaine to dimethylglycine conversion and that folate status modifies its effe...

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Bibliografski detalji
Izdano u:Nutrients
Glavni autori: Colomina, Jose M., Cavallé-Busquets, Pere, Fernàndez-Roig, Sílvia, Solé-Navais, Pol, Fernandez-Ballart, Joan D., Ballesteros, Mónica, Ueland, Per M., Meyer, Klaus, Murphy, Michelle M.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084009/
https://ncbi.nlm.nih.gov/pubmed/27735840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu8100621
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