Defective expression of gp180, a novel CD8 ligand on intestinal epithelial cells, in inflammatory bowel disease.

Previous studies support a role for intestinal epithelial cells (IEC) as antigen-presenting cells in mucosal immune responses. T cells activated by IEC are CD8+, suppressor in function, and dependent upon CD8-associated p56lck activation. A 180-kD glycoprotein (gp180) recognized by mAbs B9 and L12 h...

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發表在:	J Clin Invest
Principais autores:	Toy, L S, Yio, X Y, Lin, A, Honig, S, Mayer, L
格式:	Artigo
語言:	Inglês
出版:	American Society for Clinical Investigation 1997
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508397/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9329971/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119739
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