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A pharmacogenetic approach to blood pressure in Lyon hypertensive rats. A chromosome 2 locus influences the response to a calcium antagonist.

In a backcross population (n = 281) derived from a cross of the Lyon hypertensive rat with Lyon normotensive rat, we investigated whether genetic factors influence the acute cardiovascular responses to pharmacological modulation of the renin-angiotensin system, the sympathetic nervous system, and th...

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Bibliographic Details
Main Authors: Vincent, M, Samani, N J, Gauguier, D, Thompson, J R, Lathrop, G M, Sassard, J
Format: Artigo
Language:Inglês
Published: 1997
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC508389/
https://ncbi.nlm.nih.gov/pubmed/9329963
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