Thyroid hormone improves function and Ca2+ handling in pressure overload hypertrophy. Association with increased sarcoplasmic reticulum Ca2+-ATPase and alpha-myosin heavy chain in rat hearts.

We asked whether thyroid hormone (T4) would improve heart function in left ventricular hypertrophy (LVH) induced by pressure overload (aortic banding). After banding for 10-22 wk, rats were treated with T4 or saline for 10-14 d. Isovolumic LV pressure and cytosolic [Ca2+] (indo-1) were assessed in p...

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Publicado en:	J Clin Invest
Principais autores:	Chang, K C, Figueredo, V M, Schreur, J H, Kariya, K, Weiner, M W, Simpson, P C, Camacho, S A
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 1997
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508357/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9312172/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119699
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