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Novel autocrine feedback control of catecholamine release. A discrete chromogranin a fragment is a noncompetitive nicotinic cholinergic antagonist.

Catecholamine secretory vesicle core proteins (chromogranins) contain an activity that inhibits catecholamine release, but the identity of the responsible peptide has been elusive. Size-fractionated chromogranins antagonized nicotinic cholinergic-stimulated catecholamine secretion; the inhibitor was...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Mahata, S K, O'Connor, D T, Mahata, M, Yoo, S H, Taupenot, L, Wu, H, Gill, B M, Parmer, R J
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1997
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508344/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9294131/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119686
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