Survey of the Anti-Factor IX Immunoglobulin Profiles in Patients With Hemophilia B Using a Fluorescence-Based Immunoassay

BACKGROUND: Hemophilia B (HB) is an inherited bleeding disorder caused by the absence or dysfunction of coagulation factor IX (FIX). A subset of patients who have HB develop neutralizing alloantibodies (inhibitors) against FIX following infusion therapy. HB prevalence and the proportion of patients...

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Détails bibliographiques
Publié dans:J Thromb Haemost
Auteurs principaux: Boylan, Brian, Rice, Anne S., Neff, Anne T., Manco-Johnson, Marilyn J., Kempton, Christine L., Miller, Connie H.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083216/
https://ncbi.nlm.nih.gov/pubmed/27501440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13438
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